Benzenesulfonyl chloride, 3,4-dichloro- → 3,4-dichloro-N-[5-chloro-2-(methylthio)phenyl]benzenesulfonamide

HRID 70345

반응식

HRID 70345 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9]([CH3:11])=O)=[C:6]([CH:8]=1)[NH2:7].[Cl:12][C:13]1[CH:14]=[C:15]([S:20](Cl)(=[O:22])=[O:21])[CH:16]=[CH:17][C:18]=1[Cl:19]>>[Cl:12][C:13]1[CH:14]=[C:15]([S:20]([NH:7][C:6]2[CH:8]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[S:9][CH3:11])(=[O:21])=[O:22])[CH:16]=[CH:17][C:18]=1[Cl:19]

참가 물질

3

반응물 2

HCID 7383Benzenesulfonyl chloride, 3,4-dichloro-HCID 679728505-Chloro-2-(methylsulfinyl)aniline2회

생성물 1

HCID 679722173,4-dichloro-N-[5-chloro-2-(methylthio)phenyl]benzenesulfonamide수율 21.4%

실험 절차

Following General Procedure B, the title compound (52 mg, 21%) was prepared from 5-chloro-2-(methylsulfinyl)aniline (Intermediate 2) (120 mg, 0.635 mmol) and 3,4-dichlorobenzene-1-sulfonyl chloride (156 mg, 0.635 mmol).

출처 및 근거

ORD 기록
ord-a6728c0286504da2934217103634da1f
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

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