Methyl 2-bromo-4-fluoro-5-nitrophenoxyformate → HCID 14370869, 화합물
반응식
[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[N+:14]([O-])=O.[H][H]>[Pt](=O)=O.C(O)C>[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[NH2:14]참가 물질
5
실험 절차
To an ethanol solution (300 ml) of 2-fluoro-4-bromo-5-methoxycarbonyloxy nitrobenzene (30.4 g, 0.1 mol) was added platinum dioxide (1.0 g) and the mixture was stirred under a hydrogen atmosphere until no hydrogen was absorbed. After the removal of the catalyst by filtration, the solvent of the filtrate was evaporated under reduced pressure to give a brown solid (28.0 g) of 2-fluoro-4-bromo-5-methoxycarbonyloxy aniline.
후처리
- customwas absorbed
- customAfter the removal of the catalyst
- filtrationby filtration
- customthe solvent of the filtrate was evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-fc157a915ba443ac930c534e16c3ad6b
- 출처 데이터셋
- uspto-grants-1991_01
- 특허 번호
- US04983751
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