Potassium Carbonate → 5-Fluoro-2-((3-nitrobenzyl)thio)aniline
반응식
[NH2:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[SH:9].Br[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[F:8][C:6]1[CH:5]=[CH:4][C:3]([S:9][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)=[C:2]([CH:7]=1)[NH2:1]참가 물질
5
실험 절차
Following General Procedure A, the title compound (460 mg, 97%) was prepared from 2-amino-4-fluorobenzenethiol (562 g, 3.93 mmol), 1-(bromomethyl)-3-nitrobenzene (566 mg, 2.62 mmol), K2CO3 (1.8 g, 13.10 mmol) in DMF (10 ml).
출처 및 근거
- ORD 기록
- ord-697136108b5845e3b32265b19abeb3d1
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08822530B2
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