Hydrogen Bromide → (4-Bromo-2-methylbutan-2-yl)benzene

반응식

[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[CH2:3][CH2:4]O.O.[BrH:14]>>[Br:14][CH2:4][CH2:3][C:2]([CH3:6])([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:1]

참가 물질

반응물 3

HCID 260Hydrogen Bromide

HCID 962Water

HCID 2324603-Methyl-3-phenylbutan-1-ol

생성물 1

HCID 244007(4-Bromo-2-methylbutan-2-yl)benzene

실험 절차

3-Metyl-3-phenylbutanol (0.82 g) was refluxed in 47% hydrobromic acid (5 ml) under heating for 7 hours. To the reaction solution was added water and the solution was extracted with ether. After washing with a saturated aqueous solution of sodium chloride, the ether layer was dried over anhydrous magnesium sulfate, and the residue was then subjected to silica gel column chromatography. Elution with a hexane - ethyl acetate 10:1) mixture gave 1.02 of 1-bromo-3-methyl-3-phenylbutane.