Diethylamine → 3-Bromo-n,n-diethylpropanamide

HRID 70447

반응식

HRID 70447 반응식
[Br:1][CH2:2][CH2:3][C:4](Cl)=[O:5].[CH2:7]([NH:9][CH2:10][CH3:11])[CH3:8]>C1COCC1>[Br:1][CH2:2][CH2:3][C:4]([N:9]([CH2:10][CH3:11])[CH2:7][CH3:8])=[O:5]

참가 물질

4

반응물 2

HCID 8021DiethylamineHCID 84944Propanoyl chloride, 3-bromo-

생성물 1

HCID 2261123-Bromo-n,n-diethylpropanamide

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

반응 조건

온도
0 °C

실험 절차

A mixture of 3-bromopropanoyl chloride (1.0 g, 5.8 mmol) and diethylamine (1.9 g, 26 mmol) in THF (20 ml) was stirred at 0° C. for 30 min, the resulting white solid was filtered and the filtrate was concentrated to give a crude oil which was used in the next reaction without further purification.

후처리

  1. filtrationthe resulting white solid was filtered
  2. concentrationthe filtrate was concentrated
  3. customto give a crude oil which
  4. customwas used in the next reaction without further purification

출처 및 근거

ORD 기록
ord-bb963a68e9dd4b3f84fe5e6051568428
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

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