Sodium Hydroxide → HCID 9815420, 화합물

HRID 704551노트

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HRID 704551 반응식
[OH-].[Na+].[N:3]1([CH2:8][C:9]#[C:10][CH2:11][NH:12][C:13]([NH:15]C(=O)C2C=CC=CC=2)=[O:14])[CH2:7][CH2:6][CH2:5][CH2:4]1>>[N:3]1([CH2:8][C:9]#[C:10][CH2:11][NH:12][C:13]([NH2:15])=[O:14])[CH2:4][CH2:5][CH2:6][CH2:7]1

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 15167055HCID 15167055, 화합물

생성물 1

HCID 9815420HCID 9815420, 화합물

실험 절차

To a solution of sodium hydroxide (0.1 mol) at 80° C. is added N-[[[4-(1-pyrrolidinyl)-2-butynyl]amino]-carbonyl]-benzamide (4.3 g, 0.015 mol) (Example 1f) in one portion. The solution is allowed to stir for 12 minutes, cooled, extracted with chloroform, dried over magnesium sulfate and concentrated to give an oil which solidifies upon standing; mp 71°-73° C.

후처리

  1. temperaturecooled
  2. extractionextracted with chloroform
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated
  5. customto give an oil which

출처 및 근거

ORD 기록
ord-a49f4496bb6d494aacac8bd4e60fca60
출처 데이터셋
uspto-grants-1991_01
특허 번호
US04988688

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