Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 70498생성일: 2026년 10월 25일
(5-Chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol → HCID 58452560, 화합물
https://huagongshe.com/reaction/70498
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (5-Chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol | HCID 67396108 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | HCID 58452560 | HCID 58452560 | 72.3% |
반응 단계
Manganese dioxide (8.34 g) was added to a solution of (5-chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol (1.42 g) in chloroform (40 mL), and the mixture was stirred at 65° C. for one hour. The reaction solution was filtered through celite and the filtrate was concentrated. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1→1:1) to give the title compound as a yellow powder (1.02 g, 71%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08822503B2 |
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| 출처 데이터셋 | uspto-grants-2014_09 |
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| ORD ID | ord-05aa97b3d97643d39956e86c0a758c43 |
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| 출처 메모 | uspto-grants-2014_09 |
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