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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 70498생성일: 2026년 10월 25일

(5-Chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol → HCID 58452560, 화합물

https://huagongshe.com/reaction/70498

반응식

참여 물질

역할이름HCID투입량
반응물(5-Chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanolHCID 67396108—
촉매HCID 178418406HCID 178418406—
용매ChloroformHCID 6212—
생성물HCID 58452560HCID 5845256072.3%

반응 조건

온도65 °C

반응 단계

Manganese dioxide (8.34 g) was added to a solution of (5-chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol (1.42 g) in chloroform (40 mL), and the mixture was stirred at 65° C. for one hour. The reaction solution was filtered through celite and the filtrate was concentrated. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1→1:1) to give the title compound as a yellow powder (1.02 g, 71%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08822503B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-05aa97b3d97643d39956e86c0a758c43
출처 메모uspto-grants-2014_09