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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 706660생성일: 2026년 10월 25일

3-methyl-1-((6-methylpyridin-2-yl)methyl)-4-nitro-1H-indazole → 3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-amine

https://huagongshe.com/reaction/706660

반응식

참여 물질

역할이름HCID투입량
반응물3-methyl-1-((6-methylpyridin-2-yl)methyl)-4-nitro-1H-indazoleHCID 67259299—
촉매Palladium hydroxideHCID 9942167—
용매EthanolHCID 702—
생성물3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-amineHCID 6726093875.1%

반응 단계

A suspension of 3-methyl-1-((6-methylpyridin-2-yl)methyl)-4-nitro-1H-indazole (54 mg, 0.19 mmol) in absolute EtOH (1.5 mL) was treated at ambient temperature with 10% palladium hydroxide on carbon (27 mg, 0.019 mmol). The mixture was stirred at ambient temperature under a hydrogen atmosphere for 16 hours, and then filtered through a Celite® pad, washing with EtOH. The filtrate was concentrated under reduced pressure to afford the product (36 mg) as a yellow oil.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09174981B2
출처 데이터셋uspto-grants-2015_11
ORD IDord-ccd8ef8d898f4478bffd9b68217a7e77
출처 메모uspto-grants-2015_11