Water → 3,6-Dibromobenzene-1,2-diamine

HRID 70750

반응식

HRID 70750 반응식
[Br:1][C:2]1[C:10]2[C:6](=[N:7]S[N:9]=2)[C:5]([Br:11])=[CH:4][CH:3]=1.[BH4-].[Na+].O>C(O)C>[Br:1][C:2]1[C:10]([NH2:9])=[C:6]([NH2:7])[C:5]([Br:11])=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 6263614,7-Dibromo-2,1,3-benzothiadiazoleHCID 4311764Sodium borohydride

생성물 1

HCID 118215323,6-Dibromobenzene-1,2-diamine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The specific preparation is described as follows: dissolving 4,7-dibromo-2,1,3-benzothiadiazole in organic solvent such as ethanol, adding appropriate sodium borohydride at 0° C., then raising the temperature to room temperature, stirring for 12-24 hours, distilling organic solvent of reaction product, after adding water, washing with saline water, then extracting with diethyl ether, drying with anhydrous sodium sulfate. 3,6-dibromo-1,2-diaminobenzene is obtained after solvent is rotary dried.

후처리

  1. customThe specific preparation
  2. distillationdistilling organic
  3. customsolvent of reaction product
  4. washwashing with saline water
  5. extractionextracting with diethyl ether
  6. dry with materialdrying with anhydrous sodium sulfate

출처 및 근거

ORD 기록
ord-869ba25368eb494f825ec82fe352d855
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822634B2

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