Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 708787

반응식

HRID 708787 반응식
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

생성물 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vacuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

후처리

  1. customSolvents were evaporated
  2. customdried under vacuo

출처 및 근거

ORD 기록
ord-051aa11aea3d49acb73551ed03209563
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09175003B2

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