Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropyl Ether → HCID 178511829, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropyl Ether | HCID 7914 | — |
| 반응물 | P-Coumaric Acid | HCID 637542 | — |
| 반응물 | Sitagliptin | HCID 4369359 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178511829 | HCID 178511829 | — |
반응 단계
Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in methanol (12 ml) at 60° C. to 65° C. and the solution was cooled to room temperature. Isopropyl ether (240 ml) was added to the resultant clear solution and stirred for 14 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181256B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-b433bb3107814315a15bc68ab198b2e5 |
| 출처 메모 | uspto-grants-2015_11 |