N-Iodosuccinimide → HCID 178516695, 화합물
반응식
[S:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][C:8]=2[OH:10])[CH:3]=[CH:2]1.[I:11]N1C(=O)CCC1=O>C(#N)C>[I:11][C:7]1[C:8]([OH:10])=[C:9]2[S:1][CH:2]=[CH:3][C:4]2=[N:5][CH:6]=1참가 물질
4
실험 절차
A mixture of thieno[3,2-b]pyridin-7-ol (from Aldrich) (0.54 g, 3.6 mmol) and N-iodosuccinimide (0.88 g, 3.9 mmol) in acetonitrile (10 mL) was heated at reflux overnight. The mixture was concentrated under reduced pressure to give the desired product which was used in the next step without further purification. LCMS calculated for C7H5INOS (M+H)+: m/z=277.9. Found: 277.8.
후처리
- temperaturewas heated
- temperatureat reflux overnight
- concentrationThe mixture was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-ea054b2c91ae4a20a0453632b40f7930
- 출처 데이터셋
- uspto-grants-2015_11
- 특허 번호
- US09181271B2
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