2,4-Dichloro-5-fluoropyrimidine → HCID 11552202, 화합물

HRID 71389

반응식

Cl[C:2]1[N:7]=[C:6](Cl)[C:5]([F:9])=[CH:4][N:3]=1.[NH2:10][C:11]1[CH:19]=[C:18]2[C:14]([CH:15]=[CH:16][NH:17]2)=[CH:13][CH:12]=1>>[NH:17]1[C:18]2[C:14](=[CH:13][CH:12]=[C:11]([NH:10][C:2]3[N:7]=[C:6]([NH:10][C:11]4[CH:19]=[C:18]5[C:14]([CH:15]=[CH:16][NH:17]5)=[CH:13][CH:12]=4)[C:5]([F:9])=[CH:4][N:3]=3)[CH:19]=2)[CH:15]=[CH:16]1

참가 물질

반응물 2

HCID 2507052,4-Dichloro-5-fluoropyrimidine

HCID 2560966-Aminoindole

생성물 1

HCID 11552202HCID 11552202, 화합물

실험 절차

In like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 6-aminoindole were reacted to yield N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 22.39 min.; purity: 85%; MS (m/e): 359 (MH+).

후처리

customwere reacted

출처 및 근거

ORD 기록: ord-c5d6cd33bab749568bda38be0e12e289
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08822685B2

연결된 노트

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