Magnesium Stearate → Clonidine

반응식

[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1.Cl.OP([O-])([O-])=O.[Ca+2].C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>>[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1

참가 물질

반응물 3

HCID 11177Magnesium Stearate

HCID 20179Clonidine Hydrochloride

HCID 24441Calcium hydrogen phosphate

생성물 1

HCID 2803Clonidine

실험 절차

Basically 0.1 mg (base equivalent) of clonidine hydrochloride was blended with 13 mg of calcium phosphate dibasic, with 15 mg of microcrystalline cellulose, with 40 mg of hydroxypropyl methyl cellulose, 1 mg of colloidal silica and 0.9 mg of magnesium stearate.

출처 및 근거

ORD 기록: ord-3dcf1e25c5e44415a5fca05c8929c813
출처 데이터셋: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09192599B2

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