2,4-Dimethyl-3-cyclohexene carboxaldehyde → HCID 86702760, 화합물

HRID 718510

반응식

[Br-].[CH2:2]([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:29][CH:30]1[CH:35]=[C:34]([CH3:36])[CH2:33][CH2:32][CH:31]1[CH:37]=O>>[CH3:29][CH:30]1[CH:35]=[C:34]([CH3:36])[CH2:33][CH2:32][CH:31]1[CH:37]=[CH:2][CH2:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

참가 물질

반응물 2

HCID 933752,4-Dimethyl-3-cyclohexene carboxaldehyde

HCID 10863251Phenethyltriphenylphosphonium bromide

생성물 1

HCID 86702760HCID 86702760, 화합물수율 61.4%

실험 절차

Starting from phenethyltriphenylphosphonium bromide (3.67 g, 8.20 mmol, 1.0 equiv.), n-Buli (1.6 M in hexanes, 5.1 mL, 8.20 mmol, 1.0 equiv.) and 2,4-dimethylcyclohex-3-enecarbaldehyde (1.70 g, 12.3 mmol, 1.5 equiv.), 1.14 g (61%) of the title compound as a colorless oil was obtained after purification by flash chromatography on SiO2 (cyclohexane).

출처 및 근거

ORD 기록: ord-fd3b54b74f0940d2840aa364e43a0061
출처 데이터셋: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09193935B2

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