4-Methylmorpholine → 2-[2-[2-Ethyl-4-(1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)piperazin-1-yl]-(4-chlorobenzyl)-2-oxo-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

반응식

[ClH:1].[NH2:2][CH:3](CC1C=CC(Cl)=CC=1)[C:4]([N:6]1[CH2:11][CH2:10][N:9]([CH:12]([CH2:17][C:18]2[CH:27]=[CH:26][C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH:19]=2)[C:13]([NH:15][CH3:16])=[O:14])[CH2:8][CH:7]1[CH2:28][CH3:29])=[O:5].[C:38]([N:45]1[CH2:52][CH2:51][CH2:50][C@H:46]1[C:47]([OH:49])=O)([O:40][C:41]([CH3:44])([CH3:43])[CH3:42])=[O:39].[CH3:53]N(C)CCCN=C=NCC.ON1[C:69]2[CH:70]=[CH:71][CH:72]=[CH:73][C:68]=2N=N1.CN1CCOCC1>CN(C=O)C.O.CCOC(C)=O>[C:41]([O:40][C:38]([N:45]1[CH2:52][CH2:51][CH2:50][CH:46]1[C:47](=[O:49])[N:2]([CH2:53][C:68]1[CH:73]=[CH:72][C:71]([Cl:1])=[CH:70][CH:69]=1)[CH2:3][C:4]([N:6]1[CH2:11][CH2:10][N:9]([CH:12]([C:13](=[O:14])[NH:15][CH3:16])[CH2:17][C:18]2[CH:27]=[CH:26][C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH:19]=2)[CH2:8][CH:7]1[CH2:28][CH3:29])=[O:5])=[O:39])([CH3:42])([CH3:43])[CH3:44]