Malononitrile → N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

HRID 720462

반응식

HRID 720462 반응식
[NH:1]([C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].[C:13](#[N:17])[CH2:14][C:15]#[N:16]>C(O)C.N1CCCCC1>[C:15]([C:14]([C:13]#[N:17])=[CH:9][C:8]1[CH:11]=[CH:12][C:5]([NH:1][C:2](=[O:3])[CH3:4])=[CH:6][CH:7]=1)#[N:16]

참가 물질

5

반응물 2

HCID 8010MalononitrileHCID 739424-Acetamidobenzaldehyde

생성물 1

HCID 33296N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

시약·촉매·용매 2

HCID 8082Piperidine촉매HCID 702Ethanol용매

실험 절차

32.6 g (0.2 mol) of 4-acetaminobenzaldehyde and 13.74 g (0.208 mol) of malononitrile are initially charged in 140 ml of ethanol, and 24 drops of piperidine are added. The mixture is stirred at reflux for 30 min. After cooling, the crystals are filtered off with suction and dried.

후처리

  1. temperatureat reflux for 30 min
  2. temperatureAfter cooling
  3. filtrationthe crystals are filtered off with suction
  4. customdried

출처 및 근거

ORD 기록
ord-cb0e9c695341411c89b66107140370ec
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07135486B1

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