4-Bromoanisole → 1,1'-Biphenyl, 4,4'-dimethoxy-

HRID 72081

반응식

HRID 72081 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](Br)=[CH:5][CH:4]=1.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:15]2[CH:16]=[CH:17][C:12]([O:11][CH3:10])=[CH:13][CH:14]=2)=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 77304-BromoanisoleHCID 201262(4-Methoxyphenyl)boronic acid

생성물 1

HCID 164841,1'-Biphenyl, 4,4'-dimethoxy-수율 87%

실험 절차

From 4-methoxy-bromobenzene and 4-methoxyphenyl boronic acid, yield 87%; mp 178-180° C. (lit.,1 179-180° C.); IR: 1599, 1493, 1466 and 1290; 1H NMR (400 MHz; CDCl3): 7.47 (4H, d, J 8.7), 6.96 (4H, d, J 8) and 3.84 (6H, s); 13C NMR (CDCl3): 159.1, 133.9, 128.1, 114.5 and 55.7; m/z (EI) 214 (100%, M+), 171 (70), 128 (50) and 69 (40)(Found: M+, 214.099. C14H14O2 requires M, 214.099).

후처리

  1. custommp 178-180° C. (lit.,1 179-180° C.)

출처 및 근거

ORD 기록
ord-5098d817417d43229234288d64586902
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08828902B2

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