2-Chloro-4,5-difluorobenzoyl Isocyanate → HCID 178488186, 화합물

HRID 722202

반응식

HRID 722202 반응식
[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[CH3:15][O:16][C:17]1[CH:22]=[C:21]([C:23]2[NH:27][C:26]([CH3:28])=[N:25][N:24]=2)[CH:20]=[CH:19][C:18]=1[NH2:29]>C(#N)C>[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([NH:6][C:7]([NH:29][C:18]1[CH:19]=[CH:20][C:21]([C:23]2[NH:27][C:26]([CH3:28])=[N:25][N:24]=2)=[CH:22][C:17]=1[O:16][CH3:15])=[O:8])=[O:5]

참가 물질

4

반응물 2

HCID 115575832-Chloro-4,5-difluorobenzoyl IsocyanateHCID 178488184HCID 178488184, 화합물

생성물 1

HCID 178488186HCID 178488186, 화합물

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

The solution of equivalent amounts of 2-chloro-4,5-difluorobenzoyl isocyanate was added dropwise to the solution of 30 mg of 2-methoxy-4-(5-methyl-4H-[1,2,4]triazol-3-yl)phenylamine in 3 ml of acetonitrile and the mixture was stirred at room temperature for 30 minutes. The solid was then filtered off with suction, stirred with isopropanol and dried under reduced pressure.

후처리

  1. filtrationThe solid was then filtered off with suction
  2. stirringstirred with isopropanol
  3. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-9d63ce9c4ae741549cc6f9bc5d723dc6
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138414B2

연결된 노트

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