5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-amine → 5-(2-Aminophenyl)-1,3,4-oxadiazol-2-amine

HRID 722219

반응식

HRID 722219 반응식
[H][H].[N+:3]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[O:16][C:15]([NH2:17])=[N:14][N:13]=1)([O-])=O>>[NH2:3][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[O:16][C:15]([NH2:17])=[N:14][N:13]=1

참가 물질

3

반응물 2

HCID 7120425-(2-Nitrophenyl)-1,3,4-oxadiazol-2-amineHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 50938855-(2-Aminophenyl)-1,3,4-oxadiazol-2-amine

실험 절차

Hydrogen was introduced at atmospheric pressure into the solution of 350 mg of 5-(2-nitrophenyl)-[1,3,4]oxadiazol-2-ylamine until the theoretical amount had been taken up. After filtering off the catalyst with suction and concentrating the mixture under reduced pressure, the remaining oily residue was purified by column chromatography (solvent: 95:5 dichloromethane/methanol; silica gel).

후처리

  1. filtrationAfter filtering off the catalyst with suction
  2. concentrationconcentrating the mixture under reduced pressure
  3. customthe remaining oily residue was purified by column chromatography (solvent: 95:5 dichloromethane/methanol; silica gel)

출처 및 근거

ORD 기록
ord-d726a4112522467aa7270fe17a87f474
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138414B2

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