Ethyl Acetate → 2-Pyridinemethanol, 2-acetate

HRID 722240

반응식

HRID 722240 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N+:3]=1[O-].CC[O:11][C:12]([CH3:14])=[O:13]>C(OC(=O)C)(=O)C>[C:12]([O:13][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1)(=[O:11])[CH3:14]

참가 물질

4

반응물 2

HCID 8857Ethyl AcetateHCID 136022-Methylpyridine 1-oxide

생성물 1

HCID 138812-Pyridinemethanol, 2-acetate

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A solution of the 2-methylpyridine N-oxide (1.0 mmol) in acetic anhydride (5 mL) was heated to reflux for 0.5 h. Work-up (EtOAc), drying (MgSO4), evaporation and purification by preparative TLC or flash chromatography afforded the 2-(acetoxymethyl) pyridine.

후처리

  1. temperatureto reflux for 0.5 h
  2. customdrying
  3. custom(MgSO4), evaporation and purification by preparative TLC or flash chromatography

출처 및 근거

ORD 기록
ord-f83b1c34a6e84d08b42a25dcbe21d002
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138402B2

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