(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HRID 723303노트

반응식

HRID 723303 반응식
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[C:13]([N:21]1[CH2:25][CH2:24][CH:23](O)[CH2:22]1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[C:13]([N:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4]

참가 물질

4

반응물 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 9920605HCID 9920605, 화합물

생성물 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal수율 3%HCID 9668001-Benzoylpyrrolidine

실험 절차

It has been found that presence of 2–3% glucose in the reaction mixture increases the yield. As shown in table 7, 73% of N-benzoyl-3-hydroxypyrrolidine can be obtained by hydroxylation of N-benzoylpyrrolidine (2 mM) with 3.9 g/L of cells of HXN-200 in the presence of glucose (3%).

후처리

  1. temperatureincreases the yield

출처 및 근거

ORD 기록
ord-6ca740afb7ae4d8393dd5c085f1ffbf2
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07141412B2

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