Sodium hydride → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl 3-pyridinylsulfonylcarbamate

반응식

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([S:7]([NH2:10])(=[O:9])=[O:8])[CH:2]=1.[H-].[Na+].[C:13](=O)([O:39]C1C=CC=CC=1)[O:14][CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]2[C:27]3[CH:28]=[C:29]([Cl:36])[C:30]([C:32]([F:35])([F:34])[F:33])=[CH:31][C:26]=3[N:25]=[C:24]2[CH2:37][CH3:38])=[CH:19][CH:18]=1>CN(C=O)C.C(OCC)(=O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([S:7]([NH:10][C:13](=[O:39])[O:14][CH2:15][CH2:16][C:17]2[CH:18]=[CH:19][C:20]([N:23]3[C:27]4[CH:28]=[C:29]([Cl:36])[C:30]([C:32]([F:33])([F:35])[F:34])=[CH:31][C:26]=4[N:25]=[C:24]3[CH2:37][CH3:38])=[CH:21][CH:22]=2)(=[O:9])=[O:8])[CH:2]=1