3-Chlorophenol → HCID 67958317, 화합물

HRID 72473

반응식

HRID 72473 반응식
CS([O:5][CH:6]1[CH2:9][N:8]([C:10]2[N:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:11]=2[C:12]([O:14]C)=[O:13])[CH2:7]1)(=O)=O.[Cl:24][C:25]1[CH:26]=[C:27](O)[CH:28]=[CH:29][CH:30]=1>>[Cl:24][C:25]1[CH:30]=[C:29]([CH:28]=[CH:27][CH:26]=1)[O:5][CH:6]1[CH2:9][N:8]([C:10]2[N:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:11]=2[C:12]([OH:14])=[O:13])[CH2:7]1

참가 물질

3

반응물 2

HCID 79333-ChlorophenolHCID 86697871Methyl 2-(3-((methylsulfonyl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinate

생성물 1

HCID 67958317HCID 67958317, 화합물수율 88.4%

실험 절차

The title compound (D124) (85 mg) was prepared according to the experimental procedure described in Description 103A starting from methyl 2-(3-((methylsulfonyl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinate (D68) (100 mg, 0.258 mmol) and 3-Chlorophenol (0.035 ml, 0.338 mmol).

출처 및 근거

ORD 기록
ord-12374997667c4aee9c09d06757e67123
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08828987B2

연결된 노트

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