Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Phenylmethoxy)benzenemethanol → 3-Benzyloxybenzyl bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Phenylmethoxy)benzenemethanol | HCID 74341 | — |
| 반응물 | Bromotrimethylsilane | HCID 76113 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Benzyloxybenzyl bromide | HCID 1502047 | — |
반응 단계
A solution of 3-benzyloxybenzyl alcohol (2.04 g) in methylene chloride (20 mL) with TMS Bromide (2.5 eq. 3.14 mL) was heated at reflux for 6 hr. After cooling, the reaction was concentrated and then reconcentrated 2× from methylene chloride. The residue was chromatographed on silica gel with 5% methylene chloride in hexane to afford 3-benzyloxybenzyl bromide (1.26 g) as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05705524 |
| 출처 데이터셋 | uspto-grants-1998_01 |
| ORD ID | ord-148bdd1a9f154f59962ee4b9f4440268 |
| 출처 메모 | uspto-grants-1998_01 |