Acetic Acid → Benzenemethanol, 4-nitro-, 1-acetate
반응식
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:12](OC(=O)C)(=[O:14])[CH3:13].C(O)(=O)C>O>[C:12]([O:9][CH2:8][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:11][CH:10]=1)(=[O:14])[CH3:13]참가 물질
5
실험 절차
7.6 g (0.05 mol) of 4-nitrobenzyl alcohol, 4.7 ml (0.05 mol) of acetic anhydride and 5.8 ml (0.1 mol) of acetic acid were introduced into a round-bottomed flask and the mixture was heated at reflux for eight hours. The reaction medium was poured into water, extracted with ethyl ether, the organic phase decanted off, dried over magnesium sulfate and evaporated. The residue was triturated in hexane, filtered and dried. 6.1 g (62%) of 4-nitrobenzyl acetate of melting point 77°-78° C. were recovered.
후처리
- temperaturethe mixture was heated
- temperatureat reflux for eight hours
- extractionextracted with ethyl ether
- customthe organic phase decanted off
- dry with materialdried over magnesium sulfate
- customevaporated
- customThe residue was triturated in hexane
- filtrationfiltered
- customdried
- custom6.1 g (62%) of 4-nitrobenzyl acetate of melting point 77°-78° C. were recovered
출처 및 근거
- ORD 기록
- ord-688eb585bdcb494e85d1a56d24f7b9a6
- 출처 데이터셋
- uspto-grants-1998_01
- 특허 번호
- US05709867
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