Hydrochloric Acid → 4-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

HRID 727843노트

반응식

HRID 727843 반응식
[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[ClH:19]>C(O)C>[ClH:19].[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 145143684-[1-(1-Imidazolyl)-butyl]-benzoic acid

생성물 1

HCID 145143694-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1.0 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid is dissolved in 20 ml of ethanol and mixed with 10 ml of concentrated hydrochloric acid. The reaction mixture is precipitated into 100 ml of water and the precipitate is suctioned off. After recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C. is obtained.

후처리

  1. customThe reaction mixture is precipitated into 100 ml of water
  2. customAfter recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C.
  3. customis obtained

출처 및 근거

ORD 기록
ord-fc283fd46dc345c19663bdc84467f22e
출처 데이터셋
uspto-grants-1991_09
특허 번호
US05045558

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