2,3-Epoxypropyl 4'-methoxyphenyl ether → HCID 14739881, 화합물

HRID 728827

반응식

HRID 728827 반응식
[O:1]1[CH:3]([CH2:4][O:5][C:6]2[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=2)[CH2:2]1.[NH2:14][CH2:15][CH2:16][NH:17][C:18](=[O:30])[C:19]1[CH:24]=[CH:23][C:22]([N:25]2[CH:29]=[CH:28][N:27]=[CH:26]2)=[CH:21][CH:20]=1>CO>[OH:1][CH:3]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1)[CH2:2][NH:14][CH2:15][CH2:16][NH:17][C:18](=[O:30])[C:19]1[CH:24]=[CH:23][C:22]([N:25]2[CH:29]=[CH:28][N:27]=[CH:26]2)=[CH:21][CH:20]=1

참가 물질

4

반응물 2

HCID 166462,3-Epoxypropyl 4'-methoxyphenyl etherHCID 14664358N-(2-Aminoethyl)-4-(1H-imidazol-1-yl)benzamide

생성물 1

HCID 14739881HCID 14739881, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of 2.39 g (13.2 mmol) 1,2-epoxy-3-(4-methoxyphenoxy)propane in 25 mL methanol is added 3.05 g (13.2 g) N-(2-aminoethyl)-4-(1H-imidazol-1-yl)benzamide. The reaction mixture is stirred under a nitrogen atmosphere for 24 h. After this time, the precipitate is collected and recrystallized from ethanol to provide the title compound.

후처리

  1. customAfter this time, the precipitate is collected
  2. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-38e8628e4cb44652858f6f795a33044a
출처 데이터셋
uspto-grants-1991_09
특허 번호
US05051423

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