Chlorosulfonic acid → HCID 14998830, 화합물

HRID 728956

반응식

HRID 728956 반응식
[Cl:1][S:2]([OH:5])(=O)=[O:3].[C:6]1([N:12]2[CH:16]=[CH:15][N:14]=[CH:13]2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>>[N:12]1([C:6]2[CH:11]=[CH:10][C:9]([S:2]([Cl:1])(=[O:5])=[O:3])=[CH:8][CH:7]=2)[CH:16]=[CH:15][N:14]=[CH:13]1

참가 물질

3

반응물 2

HCID 24638Chlorosulfonic acidHCID 815951-Phenylimidazole

생성물 1

HCID 14998830HCID 14998830, 화합물

실험 절차

To chlorosulfonic acid cooled to 0° C. in an ice bath is added portionwise 1-phenyl-1H-imidazole. Monitor the progress of the reaction bythin-layer chromatography. When the reaction is complete, quench the mixture on ice. Saturated aqueous NaHCO3 is added until the solution is no longer acidic. Extract the mixture with CH2Cl2. Dry the organic layer over anhydrous Na2SO4 and remove the solvent in vacuo to obtain the title compound.

후처리

  1. customquench the mixture on ice
  2. additionSaturated aqueous NaHCO3 is added until the solution
  3. extractionExtract the mixture with CH2Cl2
  4. dry with materialDry the organic layer over anhydrous Na2SO4
  5. customremove the solvent in vacuo

출처 및 근거

ORD 기록
ord-6cc879f52e8e41ef9074507710849770
출처 데이터셋
uspto-grants-1991_09
특허 번호
US05051422

연결된 노트

불러오는 중…