3-Methoxybenzoic Acid → Ethyl 3-(3-methoxyphenyl)-3-oxopropanoate

반응식

O=[C:2]([C:9]1SC=[CH:12][CH:13]=1)[CH2:3][C:4]([O:6][CH2:7]C)=O.S1C=CC=C1C1C=CN=C(N)N=1.C[C:27]1([CH3:35])[O:32][C:31](=[O:33])[CH2:30][C:29](=[O:34])O1.COC1C=C(C=CC=1)C(O)=O>>[O:34]=[C:29]([C:13]1[CH:9]=[CH:2][CH:3]=[C:4]([O:6][CH3:7])[CH:12]=1)[CH2:30][C:31]([O:32][CH2:27][CH3:35])=[O:33]

참가 물질

반응물 4

HCID 114613-Methoxybenzoic Acid

HCID 162492,2-Dimethyl-1,3-dioxane-4,6-dione

HCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

HCID 27644074-(Thiophen-2-yl)pyrimidin-2-amine

생성물 1

HCID 2759696Ethyl 3-(3-methoxyphenyl)-3-oxopropanoate

실험 절차

This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 3-methoxybenzoic acid.