4-Fluorobenzoic Acid → Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate

HRID 729933

반응식

HRID 729933 반응식
O=C(C1SC=CC=1)CC(OCC)=O.S1C=CC=C1C1C=CN=C(N)N=1.C[C:27]1([CH3:35])[O:32][C:31](=[O:33])[CH2:30][C:29](=[O:34])O1.[F:36][C:37]1[CH:45]=[CH:44][C:40](C(O)=O)=[CH:39][CH:38]=1>>[F:36][C:37]1[CH:45]=[CH:44][C:40]([C:29](=[O:34])[CH2:30][C:31]([O:32][CH2:27][CH3:35])=[O:33])=[CH:39][CH:38]=1

참가 물질

5

반응물 4

HCID 99734-Fluorobenzoic AcidHCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoateHCID 27644074-(Thiophen-2-yl)pyrimidin-2-amine

생성물 1

HCID 2758844Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate

실험 절차

This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 4-fluorobenzoic acid.

후처리

  1. customThis material is prepared by a method analogous to

출처 및 근거

ORD 기록
ord-61572ee9605b46209dfb9fa41ee9770b
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07582646B2

연결된 노트

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