반응식
Cl[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][C:9]([Cl:11])=[CH:10][C:4]=2[N:3]=1.[Cl:12][C:13]1[CH:14]=[N:15][CH:16]=[C:17]([Cl:25])[C:18]=1[N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[Cl:11][C:9]1[CH:8]=[CH:7][C:5]2[N:6]=[C:2]([N:22]3[CH2:23][CH2:24][N:19]([C:18]4[C:17]([Cl:25])=[CH:16][N:15]=[CH:14][C:13]=4[Cl:12])[CH2:20][CH2:21]3)[NH:3][C:4]=2[CH:10]=1참가 물질
3
실험 절차
The 2,5-dichloro-1H-benzoimidazole (0.37 g, 1.98 mmol, Example 20b) and 1-(3,5-dichloropyridin-4-yl)piperazine (0.46 g, 1.98 mmol, Maybridge) reacted under the conditions of Example 3c to give the title compound as a white solid. M.p. 258-260° C. MS (ESI, pos. ion) m/z: 382 (M+1).
출처 및 근거
- ORD 기록
- ord-10a12fecc7624c79a96816a7018da4ac
- 출처 데이터셋
- uspto-grants-2009_09
- 특허 번호
- US07582761B2
연결된 노트
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