Triethylamine → 1-Benzyl-5-oxopyrrolidine-3-carboaldehyde

HRID 732669노트

반응식

HRID 732669 반응식
C(N(CC)CC)C.[CH2:8]([N:15]1[CH2:19][CH:18]([CH2:20][OH:21])[CH2:17][C:16]1=[O:22])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>CS(C)=O>[CH2:8]([N:15]1[C:16](=[O:22])[CH2:17][CH:18]([CH:20]=[O:21])[CH2:19]1)[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

참가 물질

4

반응물 2

HCID 8471TriethylamineHCID 1788241-Benzyl-4-(hydroxymethyl)pyrrolidin-2-one

생성물 1

HCID 722996181-Benzyl-5-oxopyrrolidine-3-carboaldehyde

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

Triethylamine and a pyridine-sulfur trioxide complex were added to a DMSO solution of 1-benzyl-4-(hydroxymethyl)pyrrolidin-2-one and stirred at room temperature for 2Hours. Thereafter, its work-up and purification were carried out in the standard method to obtain 1-benzyl-5-oxopyrrolidine-3-carboaldehyde. EI: 203.

후처리

  1. customThereafter, its work-up and purification

출처 및 근거

ORD 기록
ord-06587b7bb10048a493338260c3185964
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07585886B2

반응 노트

불러오는 중…