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Hydrochloric Acid → HCID 68867321, 화합물

HRID 733695
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인쇄 미리보기

반응식

HRID 733695 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:10]=[CH:11][C:12]([C:19]([N:21]3[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]3)=[O:20])=[C:13]3[C:17]([CH3:18])=[CH:16][NH:15][C:14]=23)[CH:5]=[CH:6][CH:7]=1.Cl>C(OCC)(=O)C.C(OCC)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:10]=[CH:11][C:12]([C:19]([N:21]3[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]3)=[O:20])=[C:13]3[C:17]([CH3:18])=[CH:16][NH:15][C:14]=23)[CH:5]=[CH:6][CH:7]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 44475668HCID 44475668, 화합물

생성물 1

HCID 68867321HCID 68867321, 화합물수율 169.9%

시약·촉매·용매 2

HCID 3283Diethyl Ether촉매HCID 8857Ethyl Acetate용매

실험 절차

1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-piperidin-1-yl-methanone (60 mg) was suspended in warm ethyl acetate (10 ml) and treated with a solution of 1M hydrochloric acid in diethyl ether (10 drops). The mixture was evaporated and dried at 40° C. under vacuum to afford the title compound (56 mg).

후처리

  1. customThe mixture was evaporated
  2. customdried at 40° C. under vacuum

출처 및 근거

ORD 기록
ord-4171eb2c3ca9450db5183c42cbace4f7
출처 데이터셋
uspto-grants-2009_09
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07589206B2

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