Sodium Acetate → 5-(2-Amino-thiazol-4-yl)-furan-2-carboxylic acid methyl ester
반응식
[CH3:1][O:2][C:3]([C:5]1[O:6][C:7]([C:10](=O)[CH2:11]Br)=[CH:8][CH:9]=1)=[O:4].CC([O-])=O.[Na+].[NH2:19][C:20]([NH2:22])=[S:21]>CCO>[CH3:1][O:2][C:3]([C:5]1[O:6][C:7]([C:10]2[N:19]=[C:20]([NH2:22])[S:21][CH:11]=2)=[CH:8][CH:9]=1)=[O:4]참가 물질
5
실험 절차
5-(2-Bromo-acetyl)-furan-2-carboxylic acid methyl ester (0.39 g, 1.61 mmol) was treated with NaOAc (0.185 g, 2.25 mmol) and thiourea (0.12 g, 1.6 mmol) in EtOH to give 5-(2-Amino-thiazol-4-yl)-furan-2-carboxylic acid methyl ester; MS: 225.1 (M+H+).
출처 및 근거
- ORD 기록
- ord-eeceb7f1539a46c0ae78d0b7f1e6cd1e
- 출처 데이터셋
- uspto-grants-2009_09
- 특허 번호
- US07595398B2
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