Ethyl iodoacetate → (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester
반응식
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-])=O.[CH2:13]([O:15][C:16](=[O:19])[CH2:17]I)[CH3:14]>CC#N>[CH2:13]([O:15][C:16](=[O:19])[CH2:17][C:8]1[C:7]2[C:11](=[CH:12][C:4]([NH2:1])=[CH:5][CH:6]=2)[NH:10][CH:9]=1)[CH3:14]참가 물질
4
실험 절차
(6-Amino-1H-indol-3-yl)-acetic acid ethyl ester (B-17) was synthesized following the general scheme above starting from 6-nitroindole and iodo-acetic acid ethyl ester. Overall yield (24%). HPLC ret. time 0.95 min, 10-99% CH3CN, 5 min run; ESI-MS 219.2 m/z (MH+).
후처리
- customOverall yield (24%)
출처 및 근거
- ORD 기록
- ord-ed116ac2db13497eaec502a4321fada4
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08829204B2
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