Dimethylformamide dimethyl acetal → HCID 76548813, 화합물

HRID 73938노트

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HRID 73938 반응식
[CH2:1]([O:3][C:4](=[O:18])[C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[C:7]([N+:14]([O-:16])=[O:15])[C:6]=1[CH3:17])[CH3:2].CO[CH:21]([N:24]([CH3:26])[CH3:25])OC>CN(C=O)C>[CH2:1]([O:3][C:4](=[O:18])[C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[C:7]([N+:14]([O-:16])=[O:15])[C:6]=1[CH:17]=[CH:21][N:24]([CH3:26])[CH3:25])[CH3:2]

참가 물질

4

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HCID 78373Dimethylformamide dimethyl acetalHCID 43386560Ethyl 2-methyl-3,5-dinitrobenzoate

생성물 1

HCID 76548813HCID 76548813, 화합물수율 48%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

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온도
100 °C

실험 절차

A mixture of 2-methyl-3,5-dinitro-benzoic acid ethyl ester (35 g, 0.14 mol) and dimethoxymethyl-dimethyl-amine (32 g, 0.27 mol) in DMF (200 mL) was heated at 100° C. for 5 h. The mixture was poured into ice-water. The precipitate was collected via filtration and washed with water to give 2-(2-dimethylamino-vinyl)-3,5-dinitro-benzoic acid ethyl ester (11.3 g, 48%).

후처리

  1. filtrationThe precipitate was collected via filtration
  2. washwashed with water

출처 및 근거

ORD 기록
ord-e672a1539ece48a0ace0526f637ab561
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08829204B2

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