Water → 6-Butylbenzo[b]quinolizinium perchlorate

HRID 742490노트

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HRID 742490 반응식
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].CO[C:8]1[C:17]2[CH:16]=[C:15]3[CH:18]=[CH:19][CH:20]=[CH:21][C:14]3=[CH:13][N+:12]=2[CH:11]=[CH:10][CH:9]=1.O.Cl([O-])(=O)(=O)=O.[Na+]>Br>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH2:17]([C:13]1[N+:12]2[CH:11]=[CH:10][CH:9]=[CH:8][C:17]=2[CH:16]=[C:15]2[CH:18]=[CH:19][CH:20]=[CH:21][C:14]=12)[CH2:8][CH2:9][CH3:10]

참가 물질

5

반응물 3

HCID 962WaterHCID 522606Sodium PerchlorateHCID 151862871-Methoxybenzo[b]quinolizinium perchlorate

생성물 1

HCID 190474766-Butylbenzo[b]quinolizinium perchlorate수율 156.2%

시약·촉매·용매 1

HCID 260Hydrogen Bromide용매

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온도
100 °C

실험 절차

A mixture of 1-methoxybenzo[b]quinolizinium perchlorate (1.4 g; 6.1 mmol) in 30 ml of 48% HBr was heated at 100° C. for 16 hour. The reaction mixture was poured into 100 ml of water and 50 ml of sodium perchlorate was added with stirring. The resulting solid was filtered and dried to afford 1.6 g (88.8%) of 1-hydroxybenzo[b]quinolizinium perchlorate (Formula II: R1 =1--OH; R2 =R3 =H; X- =ClO4-) as a solid.

후처리

  1. additionwas added
  2. filtrationThe resulting solid was filtered
  3. customdried

출처 및 근거

ORD 기록
ord-0f48b2e88a4f4342a5d0d207fe20ae8c
출처 데이터셋
uspto-grants-1996_09
특허 번호
US05554620

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