HCID 53694269, 화합물 → HCID 13655191, 화합물
반응식
[C:1]1(=[O:28])[N:5]([CH2:6][C:7]2[CH:12]=[CH:11][C:10]([CH:13]=[CH:14][C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)=[CH:9][CH:8]=2)[C:4](=[O:23])[C:3]2=[CH:24][CH:25]=[CH:26][CH:27]=[C:2]12>C(Cl)(Cl)Cl.[C].[Pd]>[C:4]1(=[O:23])[N:5]([CH2:6][C:7]2[CH:8]=[CH:9][C:10]([CH2:13][CH2:14][C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)=[CH:11][CH:12]=2)[C:1](=[O:28])[C:2]2=[CH:27][CH:26]=[CH:25][CH:24]=[C:3]12참가 물질
4
실험 절차
Catalytic reduction of a solution of 9 g of 4-[2-(4-phthalimidomethylphenyl)ethenyl]benzonitrile in 300 ml of chloroform was carried out with 2 g of a 5% palladium-carbon as catalyst. The reaction mixture was filtered from the spent catalyst and the filtrate was concentrated under reduced pressure. Ether was added to the residue and the precipitated crystals were collected by filtration to obtain 8.5 g of 4-[2-(4-phthalimidomethylphenyl)ethyl]benzonitrile; m.p. 194°-197° C.