6-Methyltetralin → HCID 55279233, 화합물

HRID 746373노트

반응식

HRID 746373 반응식
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[CH2:8][CH2:7][CH2:6][CH2:5][C:4]=2[CH:3]=1.[Cl:12][S:13](O)(=[O:15])=[O:14]>C(Cl)(Cl)Cl>[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[CH2:8][CH2:7][CH2:6][CH2:5][C:4]=2[C:3]=1[S:13]([Cl:12])(=[O:15])=[O:14]

참가 물질

4

반응물 2

HCID 155146-MethyltetralinHCID 24638Chlorosulfonic acid

생성물 1

HCID 55279233HCID 55279233, 화합물수율 95.4%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

A solution of 20 g (0.137 mol) 2-methyl-5,6,7,8-tetrahydro-naphthalene in 200 mL CHCl3 was added to 48 g (0.412 mol) chlorosulfonic acid at 0° C. After 2 hrs at room temperature the solution was slowly poured onto ice. The organic phase was washed, dried and concentrated to give 32 g 2-methyl-5,6,7,8-tetrahydro-naphthalene-sulfonic acid chloride used directly for the subsequent reaction.

후처리

  1. additionAfter 2 hrs at room temperature the solution was slowly poured onto ice
  2. washThe organic phase was washed
  3. customdried
  4. concentrationconcentrated

출처 및 근거

ORD 기록
ord-a2a9f3a41f474effba3b49c4c1618046
출처 데이터셋
uspto-grants-2008_07
특허 번호
US07393843B2

반응 노트

불러오는 중…