Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 746661생성일: 2026년 10월 26일
2,3-Dihydroxybutanedioic Acid → (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate
https://huagongshe.com/reaction/746661
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| 반응물 | Tolterodine | HCID 443879 | — |
| 용매 | tert-Butyl methyl ether | HCID 15413 | — |
| 생성물 | (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-methylphenol 2,3-dihydroxysuccinate | HCID 9847786 | 71.9% |
반응 단계
Tolterodine free base (2.0 gm) is dissolved in methyl tert-butyl ether (25 ml), tartaric acid (1.2 gm) is added and the reaction mass is heated to 40° C. Then the contents are cooled to 25° C., maintained for 2 hours at 25° C. to 30° C. and filtered to give 2.1 gm of tolterodine tartrate form III.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07393874B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_07 |
|---|
| ORD ID | ord-f76e4e4203d24c6e953c60140ebe904d |
|---|
| 출처 메모 | uspto-grants-2008_07 |
|---|
