反应详情

温度

40 °C

Tolterodine free base (2.0 gm) is dissolved in methyl tert-butyl ether (25 ml), tartaric acid (1.2 gm) is added and the reaction mass is heated to 40° C. Then the contents are cooled to 25° C., maintained for 2 hours at 25° C. to 30° C. and filtered to give 2.1 gm of tolterodine tartrate form III.

1. temperatureThen the contents are cooled to 25° C.
2. temperaturemaintained for 2 hours at 25° C. to 30° C.
3. filtrationfiltered