2-Acetylfuran → HCID 535936, 화합물

반응식

[C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)(=[O:3])[CH3:2].CO[CH:11](OC)[N:12]([CH3:14])[CH3:13]>>[CH3:11][N:12]([CH3:14])[CH:13]=[CH:2][C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)=[O:3]

참가 물질

반응물 2

HCID 145052-Acetylfuran

HCID 78373Dimethylformamide dimethyl acetal

생성물 1

HCID 535936HCID 535936, 화합물수율 97%

반응 조건

온도: 100 °C

실험 절차

A mixture of 2-acetylfuran (25.0 g, 0.227 mol) and N,N-dimethylformamide dimethylacetal (40 ml) was stirred at 100° C. for 9 hours. After cooling as it was, the reaction mixture was concentrated. To the residue were added diethyl ether and hexane. The resulting solid was collected by filtration and washed with hexane, to give the title compound (36.5 g, 97%) as a brown solid.

후처리

temperatureAfter cooling as it
concentrationthe reaction mixture was concentrated
additionTo the residue were added diethyl ether and hexane
filtrationThe resulting solid was collected by filtration
washwashed with hexane

출처 및 근거

ORD 기록: ord-f719234000f54031b9cac03a1799a13f
출처 데이터셋: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07396836B2

반응 노트

불러오는 중…