Ethyl Acetate → (5R,5'R)-4,4'-Bis-(5-(1H-1,2,3-triazol-1-yl)methyl-2-oxo-oxazolidin-3-yl)-2,2'-difluoro-biphenyl

반응식

[F:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:16][C@H:15]([CH2:17][N:18]3[CH:22]=[CH:21][N:20]=[N:19]3)[O:14][C:13]2=[O:23])[CH:5]=[CH:6][C:7]=1[Sn](C)(C)C.Br[C:25]1S[C:27]([C:30]#N)=[CH:28][N:29]=1.[F-:32].[K+].[C:34]([O:37][CH2:38][CH3:39])(=[O:36])C>CN(C)C=O.CS(C)=O.[Cu]I.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[N:18]1([CH2:17][C@@H:15]2[O:14][C:13](=[O:23])[N:12]([C:4]3[CH:5]=[CH:6][C:7]([C:7]4[CH:30]=[CH:27][C:28]([N:29]5[CH2:25][C@H:38]([CH2:39][N:18]6[CH:22]=[CH:21][N:20]=[N:19]6)[O:37][C:34]5=[O:36])=[CH:3][C:2]=4[F:32])=[C:2]([F:1])[CH:3]=3)[CH2:16]2)[CH:22]=[CH:21][N:20]=[N:19]1