Hydrochloric Acid → HCID 22351003, 화합물

HRID 747503노트

반응식

HRID 747503 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]([CH2:21][CH2:22][CH2:23][NH:24]C(=O)OC(C)(C)C)[C:11](=[N:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[S:12][CH:13]=2)=[CH:5][CH:4]=1.Cl>O1CCOCC1>[NH2:24][CH2:23][CH2:22][CH2:21][N:10]1[C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:13][S:12][C:11]1=[N:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 22351001t-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)thiazol-3(2H)-yl]propylcarbamate

생성물 1

HCID 22351003HCID 22351003, 화합물수율 122.7%

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

A mixture of t-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)-thiazol-3(2H)-yl]propylcarbamate (400 mg) and a 4N solution of hydrogen chloride in dioxane (8 ml) was stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure, and to the residue was added diethyl ether. The insoluble salt was collected by filtration to give the title compound (379 mg) as hydrochloride.

후처리

  1. customThe solvent was evaporated under reduced pressure
  2. additionto the residue was added diethyl ether
  3. filtrationThe insoluble salt was collected by filtration

출처 및 근거

ORD 기록
ord-692a4af97287428bb06cfaada5974a65
출처 데이터셋
uspto-grants-2008_07
특허 번호
US07396842B2

반응 노트

불러오는 중…