2-(Phenylmethyl)propanedinitrile → 2-benzyl-2-((E)-3-chloro-2-propenyl)malononitrile

HRID 749569

반응식

HRID 749569 반응식
[CH2:1]([CH:8]([C:11]#[N:12])[C:9]#[N:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Na+].[Cl:15][CH:16]=[CH:17][CH2:18]Cl>CN(C)C=O>[CH2:1]([C:8]([CH2:18]/[CH:17]=[CH:16]/[Cl:15])([C:9]#[N:10])[C:11]#[N:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 158462-(Phenylmethyl)propanedinitrileHCID 24758Sodium hydrideHCID 248831,3-Dichloropropene

생성물 1

HCID 222350072-benzyl-2-((E)-3-chloro-2-propenyl)malononitrile수율 36.4%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Using 0.49 g of benzylmalononitrile, 15 ml of N,N-dimethylformamide, 0.14 g of sodium hydride (60% in oil), and 0.33 g of 1,3-dichloropropene, and according to the process described in the Production Example 1, there was obtained 0.25 g of 2-benzyl-2-((E)-3-chloro-2-propenyl)malononitrile (the present compound (60)) as high-polar compound.

출처 및 근거

ORD 기록
ord-d4b7bbe000b04ae5a60a261f8538481a
출처 데이터셋
uspto-grants-2008_07
특허 번호
US07402691B2

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