Hydrochloric Acid → HCID 178508313, 화합물
반응식
C[Si](C)(C)CCOC[N:7]1[CH:11]=[CH:10][C:9]([C:12]2[C:13]3[NH:21][N:20]=[N:19][C:14]=3[N:15]=[C:16]([NH2:18])[N:17]=2)=[N:8]1.Cl>CO>[NH:7]1[CH:11]=[CH:10][C:9]([C:12]2[C:13]3[NH:21][N:20]=[N:19][C:14]=3[N:15]=[C:16]([NH2:18])[N:17]=2)=[N:8]1참가 물질
4
실험 절차
A solution of 7-(1-(2-(trimethylsilyl)ethoxymethyl)-1H-pyrazol-3-yl)-1H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine (120 mg, 0.361 mmol) in MeOH (2 mL) was treated with HCl (4-M in dioxan, 1 mL), stirred for 2 h, filtered and the resulting solid washed with Et2O to give the title compound (76 mg, 100%) as a yellow solid.
후처리
- filtrationfiltered
- washthe resulting solid washed with Et2O
출처 및 근거
- ORD 기록
- ord-42d768a177f34cd9a45575e92eebf745
- 출처 데이터셋
- uspto-grants-2008_07
- 특허 번호
- US07405219B2
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