Benzaldehyde → HCID 178418819, 화합물

HRID 7510

반응식

HRID 7510 반응식
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.[C:7]([N+:11]#[C-:12])([CH3:10])([CH3:9])[CH3:8].[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:21]([Cl:24])(=[O:23])[CH3:22]>Cl(O)(=O)(=O)=O>[Cl-:24].[C:21]([N+:1]1[C:13]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:12]([NH:11][C:7]([CH3:10])([CH3:9])[CH3:8])[N:6]2[CH:5]=[CH:4][S:3][C:2]=12)(=[O:23])[CH3:22]

참가 물질

6

반응물 4

HCID 240BenzaldehydeHCID 21552-AminothiazoleHCID 6367Acetyl chlorideHCID 23577Tert-Butyl isocyanide

생성물 1

HCID 178418819HCID 178418819, 화합물

시약·촉매·용매 1

HCID 24247Perchloric Acid용매

실험 절차

Example 4 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-thiazole (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

출처 및 근거

ORD 기록
ord-3530e699346948b5a62efd1270abe4aa
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07087607B2

연결된 노트

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