Lithium Hydroxide → HCID 11633081, 화합물

HRID 751199

반응식

HRID 751199 반응식
C([O:3][C:4](=[O:32])[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH2:16][CH2:17][CH2:18][C:19]#[C:20][C:21]3[CH:26]=[CH:25][C:24]([O:27][C:28]([F:31])([F:30])[F:29])=[CH:23][CH:22]=3)=[CH:12][CH:13]=2)[CH:8]=[CH:7]1)C.[Li+].[OH-]>>[F:30][C:28]([F:29])([F:31])[O:27][C:24]1[CH:23]=[CH:22][C:21]([C:20]#[C:19][CH2:18][CH2:17][CH2:16][O:15][C:11]2[CH:10]=[C:9]3[C:14](=[CH:13][CH:12]=2)[N:6]([CH2:5][C:4]([OH:32])=[O:3])[CH:7]=[CH:8]3)=[CH:26][CH:25]=1

참가 물질

3

반응물 2

HCID 3939Lithium HydroxideHCID 68822255{5-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl ester

생성물 1

HCID 11633081HCID 11633081, 화합물

실험 절차

In analogy to the procedure described for example 1 e], {5-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as red crystals.

출처 및 근거

ORD 기록
ord-ec984741bb414964b10e1c460664a59b
출처 데이터셋
uspto-grants-2008_07
특허 번호
US07405236B2

연결된 노트

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