Ammonium Hydroxide → HCID 178461168, 화합물
반응식
[NH4+].[OH-].S[C:4]1[N:5]=[C:6]([OH:14])[C:7]2[C@H:12]([CH3:13])[CH2:11][CH2:10][C:8]=2[N:9]=1>[Ni].O>[CH3:13][C@H:12]1[C:7]2[C:6]([OH:14])=[N:5][CH:4]=[N:9][C:8]=2[CH2:10][CH2:11]1참가 물질
5
실험 절차
Raney Nickel (15 g) and NH4OH (20 mL) was added to a suspension of (R)-2-mercapto-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin4-ol (12 g, 65.8 mmol) in distilled water (100 mL). The mixture was refluxed for 3 hours and then filtered. The filtrate was concentrated to afford (R)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol (9.89 g, 99%). MS (APCI+) [M+H]+151.
후처리
- temperatureThe mixture was refluxed for 3 hours
- filtrationfiltered
- concentrationThe filtrate was concentrated
출처 및 근거
- ORD 기록
- ord-6ec18d5e94ec44e5a49b16a85ca04582
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08835434B2
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